Wednesday's papers

Both the Independent and the Guardian describe it as the last throw of the dice

Gordon Brown bolstered his position yesterday by unveiling a list of policy announcements aimed at securing Labour a fourth term by winning back voters in Middle England who have deserted the party.says the former

The prime minister will hope the speech, unusually rich in policy detail, finally puts paid to any leadership challenge before the next election – and translates into a lift in the polls that will stop Labour MPs panicking as the parties enter the new year.

says the Guardian

The Prime Minister promised to remodel the economy, clean up politics and create a more responsible society during a defiant performance in Brighton in which he set out the lines on which the looming election battle will be fought. He told MPs and delegates not to give in to defeatism but to “dream big dreams”. says the Times

The Telegraph reports that

Mr Brown’s combative speech at the Labour conference in Brighton was well received and appeared to have quashed speculation that he could be ousted as party leader before the election.

However maybe the biggest news maybe that the Sun has turned on the party.Its front page quite simply says

This Labour Government has lost its way. Now it’s lost The Sun’s support too

The Mail leads with the news that the cervical cancer vaccination programme was in chaos last night after the death of 14-year-old Natalie Morton.

many health trusts are cancelling vaccinations due over the next few weeks while they investigate whether vaccine stocks are linked to the dose given to Natalie, who died on Monday hours after receiving the jab.

it says despite the fact that

Last night initial post mortem results suggested the schoolgirl had a serious underlying health condition which meant it was 'unlikely' the vaccine had caused her death.

According to the Times

A young Afghan girl suffered fatal injuries after a box of public information leaflets, dropped from an RAF transport aircraft over Helmand province, landed on top of her.

Staying on the subject of Aghanistan,the Telegraph reports that the new Secretary-General of Nato, has accused America of talking down European countries' commitment to Afghanistan.

In his first speech since taking the job,Anders Fogh Rasmussen said all 28 members of the transatlantic alliance were spending their "blood and treasure" on a mission of critical importance.

Twenty-five million more children will go hungry by the middle of this century as climate change leads to food shortages and soaring prices for staples such as rice, wheat, maize and soya beans, a report says today.

reports the Guardian adding that

the report, prepared by the International Food Policy Research Institute (IFPRI) for the World Bank and Asian Development Bank.says that

If global warming goes unchecked, all regions of the world will be affected, but the most vulnerable – south Asia and sub-Saharan Africa – will be hit hardest by failing crop yields

Many of the papers report on what the Independent calls the Horror of Guinea stadium when

Thousands had marched to the football stadium in downtown Conakry on Monday to protest against Guinea's military junta. Nearly 160 people paid for that show of dissent with their lives, it emerged yesterday, some gunned down in a hail of bullets, other skewered by bayonets as they tried to flee or rescue the women being raped by soldiers in the stands.

Meanwhile natural disasters abroad as well

Up to 100 people are reported to have died after a powerful undersea earthquake struck in the South Pacific between Samoa and American Samoa.
Emergency services feared entire villages had been wiped out by the massive waves, which sent terrified residents fleeing for higher ground.reports the Mail